drugs used in obstetrics?

7.1 Drugs used in obstetrics
7.1.1 Prostaglandins and oxytocics
Induction and augmentation of labour
RED Dinoprostone vaginal gel 1mg and 2mg
RED Oxytocin injection 5units/mL, 10units/mL

Dinoprostone 10mg vaginal delivery system (Propess®)
Propess® (dinoprostone) 10mg vaginal delivery system is licensed and now locally approved for the initiation of cervical ripening in
patients, at term (from 38th week of gestation). It has a number of advantages over dinoprostone gel (Prostin®) and is expected to
become the product of choice for this indication where appropriate. This is in line with recommendations from NICE in its Clinical
Guideline advice on Induction of Labour which stated use of Propess® is expected to deliver downstream savings from its
preferential use over Prostin® gel.

RED Dinoprostone vaginal pessaries 10mg

Prevention and treatment of haemorrhage
RED Carboprost injection 250 microgram/mL
RED Ergometrine injection 500 microgram/mL
RED Oxytocin with ergometrine (Syntometrine®)

Prophylaxis of postpartum haemorrhage at caesarean section
Specific Patient Group in enhanced treatment pathway, restricted use for elective caesarean section.(hospital use only)
RED Carbetocin100mcg/mL (Pabal®)

Induction of abortion – Consultant only
RED Misoprostol tablets 200micrograms [unlicensed]

7.1.1.1 Ductus arteriosus
Maintenance of patency
RED Alprostadil intravenous solution 500 microgram/mL
RED Dinoprostone 1mg/mL 0.75mL amp [unlicensed]

Closure of ductus arteriosus
RED Indometacin injection 1mg


7.1.2 Mifepristone
RED Mifepristone tablets 200mg

7.1.3 Myometrial relaxants
RED Salbutamol solution for intravenous infusion 5mg/5mL







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